Porn is not addictive. It induces short increases of dopamine and not the sustained ones produced by cocaine and opioids.

Personal power is to have the mental fortitude to live with meaning and happiness.

Unique characteristics of the human brain let us experience suffering as extending to the past and the future, and to others.

Women with spinal cord transections experience vaginal orgasms with sensations carried by the vagus nerve.

Dominance-submission frees ourselves from the psychological pressure of pride and shame.

Mutations that increase the endocannabinoid anandamide decreased pain, but did not eliminate as completely as mutations in Nav1.7

Charlotte’s Web is a cannabis strain with high cannabidiol (CBD) used to treat children with epilepsy.

The endocannabinoids anandamide and 2-AG act as retrograde neurotransmitters in synaptic plasticity and memory formation, anxiety and pain.

THC, CBD and other cannabinoids found in marihuana act through CB1, CB2 and GPR55 receptors.

Neurons process information as excitatory and inhibitory postsynaptic potentials in dendrites that generate action potentials in the axon.

Since there is no consciousness after death, we experience nothing, so there is nothing to fear.

Mind-fucking in BDSM presents unique challenges to avoid breaking consent, trauma, and inducing learned helplessness.

Denial of free will is based on religious or mystical ideas and can have dire consequences by making it ethical to control the mind.

In transgenic mice, fluorescent reporter genes, optogenetics and DREADD are used to manipulate the function of cells.

Pain is a sensation that is not always unpleasant, while suffering is a state of being based on emotions, values and meaning.

Masochist pain activates brain areas involved in empathy, emotion and consciousness, but not in addiction.

Neuroscience explains consciousness as hierarchical properties of the mind.

This coveted state of bliss and euphoria in BDSM scenes may actually be different mental states In the BDSM community, submissive space...