Dopamine D1 receptors mediate desire. The D2 receptors mediate self-control. Addictive drugs downregulate the D2 receptors, inducing the craving and impulsivity of addiction.

Mindfulness and flow are different states of consciousness, but they both diminish the ego, decreasing craving and suffering.

The craving that causes suffering is not due to seeking pleasure, but by the demands of the ego.

The idea that we deserve the best, as well as craving happiness and virtue, are traps of the ego.