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Dopamine D2 Receptor Downregulation Is the Hallmark of Addiction (Dopamine 4)
Dopamine D1 receptors mediate desire. The D2 receptors mediate self-control. Addictive drugs downregulate the D2 receptors, inducing the craving and impulsivity of addiction.
Hermes Solenzol
6 days ago11 min read


Can dopamine be depleted from its synapses? (Dopamine 3)
The dopamine depletion that decreases mental energy can mean different alterations of the synaptic mechanisms that synthesize, store, release and eliminate dopamine.
Hermes Solenzol
Nov 69 min read


Pleasure Electrodes in the Brain (Dopamine 2)
Electrodes implanted in the reward pathway do not produce pleasure but craving.
Hermes Solenzol
Oct 107 min read


Dopamine: Why Heroin Is Addictive but Porn Is Not
Porn is not addictive. It induces short increases of dopamine and not the sustained ones produced by cocaine and opioids.
Hermes Solenzol
Aug 24, 202322 min read
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